bioXEN natural cancellous (spongiosa) and cortical bone matrix is produced by the removal of all organic components from bovine bone. The an organic bone mineral matrix has macro- and microscopic structures similar to human bone.

The proprietary manufacturing process of bioXEN allows for maintenance of the naturally occurring bone mineral structure, including macroscopic and microscopic structures. Due to this trabecular architecture with interconnecting macro and micropores, the ingrowth of new bone and associated vascularization at the site of grafting is optimized.

bioXEN may be used with autogenous bone where there is an insufficient quantity of bone to fulfill the needs of the proposed surgical procedure.

• Augmentation or reconstructive treatment of the alveolar ridge.
• Filling of infrabony periodontal defects.
• Filling of defects after root resection, apicoectomy, and cystectomy.
• Filling of extraction sockets to enhance preservation of the alveolar ridge.
• Elevation of the maxillary sinus floor.
• Filling of periodontal defects in conjunction with products intended for Guided Tissue Regeneration (GTR) and Guided Bone Regeneration (GBR).
• Filling of peri-implant defects in conjunction with products intended for Guided Bone Regeneration (GBR).

Handling: The structure of BioXEN aids in particle hydrationand delivery of the product to the defect.

Particle Distribution: BioXEN maximizes the distribution ofthe preferred particle sizing within desired ranges.

Particle Structure and Porosity: BioXEN maintains the highporosity and trabecular structure of natural mineralized boneand maximizes the potential for angiogenesis.

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